Entry	Ketone	Catalyst	Solvent	Additives	Temp (˚C)	Time (h)	Yield(%)^b	dr [syn/anti]^c	ee (%)^d
1	n = 3	2	CH₃CN	–	25	48	55	93:7	3
2	n = 3	4	CH₃CN	–	25	48	40	95:5	10
3	n = 3	4	CH₃CN	–	5	90	35	95:5	15
4	n = 3	4	CH₃CN	–	-15	144	29	96:4	60
5	n = 3	5	CH₃CN	–	25	120	86	91:9	79
6	n = 3	5^e	CH₃CN	–	25	220	76	90:10	77
7	n = 3	5	CH₃CN	H₂O	25	48	61	90:10	86
8	n = 3	5	CH₃CN	AcOH	25	48	85	89:11	88
9	n = 3	5	CH₃CN	CF₃CO₂H	25	104	53	90:10	65
10	n = 3	5	iPrOH	AcOH	25	120	63	96:4	79
11	n = 3	5	iPrOH	AcOH	5	480	58	93:7	85
12	n = 3	5	toluene	–	25	65	72	90:10	87
13	n = 3	5	toluene	AcOH	25	72	35	89:11	89
14	n = 3	5	toluene	H₂O	25	48	63	91:9	89
15	n = 3	5	toluene	H₂O	5	72	87	91:9	94
16	n = 3	5	neat	–	25	65	53	95:5	85
17	n = 3	5	neat	H₂O	25	65	84	92:8	89
18	n = 3	5	neat	H₂O	5	72	84	92:8	93
19	n = 3	5	neat	AcOH	25	72	35	89:11	89
20	n = 3	6	neat	–	25	41	78	92:8	84
21	n = 3	6	neat	H₂O	25	105	93	93:7	95
22	n = 3	6	neat	AcOH	25	105	89	93:7	95
23	n = 3	6	toluene	–	25	72	62	91:9	87
24	n = 3	6	toluene	AcOH	25	72	97	93:7	86
25	n = 3	6	CH₃CN	H₂O	25	48	93	95:5	94
26	n = 3	6	CH₃CN	H₂O	5	60	84	96:4	94
27	n = 3	6	toluene	H₂O	25	68	86	94:6	75
28	n = 3	6	toluene	H₂O	5	68	81	96:4	98
29	n = 0	6	neat	H₂O	25	48	74	-	25
30	n = 0	6	neat	H₂O	5	72	68	-	29